Epigenetically mediated gene silencing (Record no. 77774)

000 -LEADER
fixed length control field 02395ngm a2200361 a 4500
001 - CONTROL NUMBER
control field HST1038_1_4
003 - CONTROL NUMBER IDENTIFIER
control field UkLoHST
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS
fixed length control field m c
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr|cna|||a||||
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field vz|czazum
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 080121s2007 enk|||||||||||s|||v|eng d
028 50 - PUBLISHER NUMBER
Publisher number 1038
Source Henry Stewart Talks
035 ## - SYSTEM CONTROL NUMBER
System control number (UkLoHST)124
035 ## - SYSTEM CONTROL NUMBER
System control number (UkLU-K)AC000390031
040 ## - CATALOGING SOURCE
Original cataloging agency UkLU-K
Language of cataloging eng
Transcribing agency UkLU-K
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Baylin, Stephen B.
Relator code spk
245 10 - TITLE STATEMENT
Title Epigenetically mediated gene silencing
Medium [electronic resource] :
Remainder of title a companion to genetic alterations in driving tumorigenesis /
Statement of responsibility, etc. Stephen Baylin.
246 3# - VARYING FORM OF TITLE
Title proper/short title Epigenetically mediated gene silencing :
Remainder of title tumorigenesis
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc. London :
Name of publisher, distributor, etc. Henry Stewart Talks,
Date of publication, distribution, etc. 2007.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (1 streaming video file (68 min.) :
Other physical details color, sound).
490 1# - SERIES STATEMENT
Series statement Epigenetics : concepts, theories, paradigms and mechanisms,
International Standard Serial Number 2056-452X
500 ## - GENERAL NOTE
General note Animated audio-visual presentation with synchronized narration.
500 ## - GENERAL NOTE
General note Title from title frames.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Contents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer.
506 ## - RESTRICTIONS ON ACCESS NOTE
Terms governing access Access restricted to subscribers.
538 ## - SYSTEM DETAILS NOTE
System details note Mode of access: World Wide Web.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Epigenesis, Genetic.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Gene Expression Regulation, Neoplastic.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Gene Silencing.
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Henry Stewart talks.
Name of part/section of a work Biomedical & life sciences collection.
-- Epigenetics : concepts, theories, paradigms and mechanisms.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/124/">https://hstalks.com/bs/124/</a>
856 42 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://hstalks.com/bs/p/18/">https://hstalks.com/bs/p/18/</a>
Materials specified Series

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