Epigenetic biomarkers in cancer [electronic resource] / Bob Brown.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.
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Mode of access: World Wide Web.