Brown, Bob,
Epigenetic biomarkers in cancer [electronic resource] / Bob Brown. - London : Henry Stewart Talks, 2012. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Biomarkers : the path forward to highly sensitive and specific molecular diagnostics, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Biomarkers. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.
Access restricted to subscribers.
Mode of access: World Wide Web.
3458 Henry Stewart Talks
Cancer--Genetic aspects.
DNA--Methylation.
Epigenesis.
Tumor markers.
DNA Methylation.
Epigenesis, Genetic.
Neoplasms--drug therapy.
Neoplasms--genetics.
Tumor Markers, Biological--genetics.
Epigenetic biomarkers in cancer [electronic resource] / Bob Brown. - London : Henry Stewart Talks, 2012. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Biomarkers : the path forward to highly sensitive and specific molecular diagnostics, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Biomarkers. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.
Access restricted to subscribers.
Mode of access: World Wide Web.
3458 Henry Stewart Talks
Cancer--Genetic aspects.
DNA--Methylation.
Epigenesis.
Tumor markers.
DNA Methylation.
Epigenesis, Genetic.
Neoplasms--drug therapy.
Neoplasms--genetics.
Tumor Markers, Biological--genetics.