Rheumatic fever [electronic resource] : a model of a post-infectious autoimmune disease / Jorge Kalil.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Autoimmune diseases | Heart -- Diseases -- Etiology | Rheumatic fever | Rheumatic heart disease | Streptococcal infections -- Complications | Vaccines -- Development | Autoimmunity | Chemokines -- immunology | Epitopes | Molecular Mimicry | Rheumatic Fever -- immunology | Rheumatic Fever -- prevention & control | Rheumatic Heart Disease -- immunology | Rheumatic Heart Disease -- prevention & control | Streptococcal Infections -- immunology | Th1 Cells | T-Lymphocytes -- immunology | VaccinationOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Autoimmunity in humans -- Infectious agents can induce breakage of tolerance to self to trigger & maintain autoimmune disease -- Rheumatic Fever & Rheumatic Heart Disease (RHD) as paradigms of post-infectious autoimmune disease -- Medical & sociological importance of RHD -- Genes involved in susceptibility -- T cell mediated autoimmunity -- Molecular mimicry -- Role of Th1 cells in human autoimmunity -- How chemokines can drive disease to different site -- Identification of autoimmune vs. anti-infection triggering epitopes -- Vaccine development to avoid infections & autoimmune disease.
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Mode of access: World Wide Web.