Kalil, Jorge,

Rheumatic fever a model of a post-infectious autoimmune disease / [electronic resource] : Jorge Kalil. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2007.

Contents: Autoimmunity in humans -- Infectious agents can induce breakage of tolerance to self to trigger & maintain autoimmune disease -- Rheumatic Fever & Rheumatic Heart Disease (RHD) as paradigms of post-infectious autoimmune disease -- Medical & sociological importance of RHD -- Genes involved in susceptibility -- T cell mediated autoimmunity -- Molecular mimicry -- Role of Th1 cells in human autoimmunity -- How chemokines can drive disease to different site -- Identification of autoimmune vs. anti-infection triggering epitopes -- Vaccine development to avoid infections & autoimmune disease.

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Mode of access: World Wide Web.

1441 Henry Stewart Talks


Autoimmune diseases.
Heart--Diseases--Etiology.
Rheumatic fever.
Rheumatic heart disease.
Streptococcal infections--Complications.
Vaccines--Development.
Autoimmunity.
Chemokines--immunology.
Epitopes.
Molecular Mimicry.
Rheumatic Fever--immunology.
Rheumatic Fever--prevention & control.
Rheumatic Heart Disease--immunology.
Rheumatic Heart Disease--prevention & control.
Streptococcal Infections--immunology.
Th1 Cells.
T-Lymphocytes--immunology.
Vaccination.
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