Genetic abnormalities in acute lymphoblastic leukemia [electronic resource] / Ching-Hon Pui.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Cancer genetics: Publisher: London : Henry Stewart Talks, 2015Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Cancer -- Genetic aspects | Genetic disorders | Lymphoblastic leukemia | Chromosome Aberrations | Genome-Wide Association Study | Neoplasms -- genetics | Polymorphism, Genetic | Precursor Cell Lymphoblastic Leukemia-Lymphoma -- drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Somatic genetic abnormalities -- Genetic classification -- Leukemogenesis -- Heterogeneity due to age of presentation, differences in cooperative mutations and target cells undergoing malignant transformation -- Genome-wide analysis disclosed novel genetic subtypes, driver mutations and targetable genetic lesions -- Germline polymorphisms and mutations affecting cancer susceptibility, treatment response and toxicity -- Precision medicine based on somatic and germline genetics.
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Mode of access: World Wide Web.