Pui, Ching-Hon,

Genetic abnormalities in acute lymphoblastic leukemia [electronic resource] / Ching-Hon Pui. - London : Henry Stewart Talks, 2015. - 1 online resource (1 streaming video file (38 min.) : color, sound). - Cancer genetics, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Cancer genetics. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Somatic genetic abnormalities -- Genetic classification -- Leukemogenesis -- Heterogeneity due to age of presentation, differences in cooperative mutations and target cells undergoing malignant transformation -- Genome-wide analysis disclosed novel genetic subtypes, driver mutations and targetable genetic lesions -- Germline polymorphisms and mutations affecting cancer susceptibility, treatment response and toxicity -- Precision medicine based on somatic and germline genetics.

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Mode of access: World Wide Web.

4049 Henry Stewart Talks


Cancer--Genetic aspects.
Genetic disorders.
Lymphoblastic leukemia.
Chromosome Aberrations.
Genome-Wide Association Study.
Neoplasms--genetics.
Polymorphism, Genetic.
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy.
Precursor Cell Lymphoblastic Leukemia-Lymphoma--genetics.
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