The pharmacokinetics of therapeutic proteins [electronic resource] / Bernd Meibohm.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Drug development | Pharmaceutical biotechnology | Pharmacokinetics | Proteins -- Therapeutic use | Antibodies, Monoclonal | Biotechnology -- methods | Drug Design | Pharmaceutical preparations -- metabolism | Pharmacology, Clinical | Proteins -- administration & dosage | Proteins -- pharmacokinetics | Proteins -- pharmacologyOnline resources: Click here to access onlineAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Differences in the pharmacokinetics of therapeutic proteins compared to small molecule drugs -- Classes of therapeutic proteins -- Central paradigm of clinical pharmacology -- Distribution and tissue penetration of mAbs and proteins -- Three methods of renal protein metabolism -- Hepatic protein metabolism -- Target-mediated drug disposition -- Immunogenicity: general considerations and contributing factors -- Neutralizing, clearing and sustaining anti-drug antibodies.
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Mode of access: World Wide Web.