Meibohm, Bernd.

The pharmacokinetics of therapeutic proteins [electronic resource] / Bernd Meibohm. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (45 min.) : color, sound). - The biomedical & life sciences collection, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Differences in the pharmacokinetics of therapeutic proteins compared to small molecule drugs -- Classes of therapeutic proteins -- Central paradigm of clinical pharmacology -- Distribution and tissue penetration of mAbs and proteins -- Three methods of renal protein metabolism -- Hepatic protein metabolism -- Target-mediated drug disposition -- Immunogenicity: general considerations and contributing factors -- Neutralizing, clearing and sustaining anti-drug antibodies.

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Mode of access: World Wide Web.

4911 Henry Stewart Talks


Drug development.
Pharmaceutical biotechnology.
Pharmacokinetics.
Proteins--Therapeutic use.
Antibodies, Monoclonal.
Biotechnology--methods.
Drug Design.
Pharmaceutical preparations--metabolism.
Pharmacology, Clinical.
Proteins--administration & dosage.
Proteins--pharmacokinetics.
Proteins--pharmacology.
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