Non-P450 oxidative metabolism [electronic resource] : characteristics and drug substrates / Christine Beedham.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Drugs -- Metabolism | Enzymes | Oxidation-reduction reaction | Oxidoreductases | Alcohol Dehydrogenase | Aldehyde Dehydrogenase | Aldehyde Oxidase | Cytochromes | Isoenzymes | Monoamine Oxidase | Monooxygenases | Oxidation Reduction | Oxidoreductases -- metabolism | Pharmaceutical Preparations -- metabolism | Reactive Oxygen Species | Substrate Specificity | Xanthine Dehydrogenase | Xanthine Oxidase | XenobioticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Non-P450 cytosolic and mitochondrial enzymes catalysing drug oxidation -- Aldehyde oxidase and xanthine oxidase -- Alcohol dehydrogenase and aldehyde dehydrogenase -- Monoamine oxidase -- Flavin monooxygenase -- Substrate specificities -- Drug and xenobiotic substrates -- Catalytic mechanism and metabolite formation -- Reactive oxygen species -- Factors affecting enzyme activity -- Polymorphism and isozymes -- Relative importance in drug metabolism.
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Mode of access: World Wide Web.