Beedham, Christine,

Non-P450 oxidative metabolism characteristics and drug substrates / [electronic resource] : Christine Beedham. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (45 min.) : color, sound). - Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2007.

Contents: Non-P450 cytosolic and mitochondrial enzymes catalysing drug oxidation -- Aldehyde oxidase and xanthine oxidase -- Alcohol dehydrogenase and aldehyde dehydrogenase -- Monoamine oxidase -- Flavin monooxygenase -- Substrate specificities -- Drug and xenobiotic substrates -- Catalytic mechanism and metabolite formation -- Reactive oxygen species -- Factors affecting enzyme activity -- Polymorphism and isozymes -- Relative importance in drug metabolism.

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Mode of access: World Wide Web.

1091 Henry Stewart Talks


Drugs--Metabolism.
Enzymes.
Oxidation-reduction reaction.
Oxidoreductases.
Alcohol Dehydrogenase.
Aldehyde Dehydrogenase.
Aldehyde Oxidase.
Cytochromes.
Isoenzymes.
Monoamine Oxidase.
Monooxygenases.
Oxidation Reduction.
Oxidoreductases--metabolism.
Pharmaceutical Preparations--metabolism.
Reactive Oxygen Species.
Substrate Specificity.
Xanthine Dehydrogenase.
Xanthine Oxidase.
Xenobiotics.
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