Statistical issues in epidemiologic studies of gene-environment interaction [electronic resource] / Peter Kraft, Donna Spiegelman.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): Environmental Exposure | Genes | Genetic Predisposition to Disease | Models, Statistical | Risk FactorsOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Gene-environment interaction in the development of human traits, including disease -- Conceptual and analytical challenges -- Joint analysis of data on both genetic and environmental factors from epidemiologic studies as a way to increase power to detect a polymorphism (or an exposure) that is associated with disease risk -- Study designs -- Statistical modeling issues in the analysis of data -- Sample size and power calculations for a range of designs -- Specification of parameters -- Ordinal coding -- Hierarchical models -- The analysis of highdimensional "pathway" data (multiple related genes and environmental exposures).
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Mode of access: World Wide Web.