Kraft, Peter.

Statistical issues in epidemiologic studies of gene-environment interaction [electronic resource] / Peter Kraft, Donna Spiegelman. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (33 min.) : color, sound). - Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Gene-environment interaction in the development of human traits, including disease -- Conceptual and analytical challenges -- Joint analysis of data on both genetic and environmental factors from epidemiologic studies as a way to increase power to detect a polymorphism (or an exposure) that is associated with disease risk -- Study designs -- Statistical modeling issues in the analysis of data -- Sample size and power calculations for a range of designs -- Specification of parameters -- Ordinal coding -- Hierarchical models -- The analysis of highdimensional "pathway" data (multiple related genes and environmental exposures).

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Mode of access: World Wide Web.

1285 Henry Stewart Talks


Environmental Exposure.
Genes.
Genetic Predisposition to Disease.
Models, Statistical.
Risk Factors.
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