Whole-genome association studies [electronic resource] : practical advice and considerations / Mike Weale.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetic epidemiology II : latest developments: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (47 min.) : color, sound)Subject(s): Genetic Predisposition to Disease -- epidemiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: What are whole-genome (genome-wide) association studies and why do them? -- Steps in WGA study -- HIV setpoint -- Phenotype definition -- Setpoint -- Whole genome genotyping panels -- PLINK -- Cryptic population stratification -- PCA and EIGENSTRAT -- SNP-by-SNP analysis -- Multiple testing approaches -- Bonferroni method -- Q-Q (quantile-quantile) plot -- False discovery rate -- Permutation -- Outright hits -- Pool of hits -- Bayesian alternatives -- Bayes factor -- Bayesian false discovery probability (BFDP).
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Mode of access: World Wide Web.