Weale, Mike.
Whole-genome association studies practical advice and considerations / [electronic resource] : Mike Weale. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (47 min.) : color, sound). - Genetic epidemiology II : latest developments, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology II : latest developments. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: What are whole-genome (genome-wide) association studies and why do them? -- Steps in WGA study -- HIV setpoint -- Phenotype definition -- Setpoint -- Whole genome genotyping panels -- PLINK -- Cryptic population stratification -- PCA and EIGENSTRAT -- SNP-by-SNP analysis -- Multiple testing approaches -- Bonferroni method -- Q-Q (quantile-quantile) plot -- False discovery rate -- Permutation -- Outright hits -- Pool of hits -- Bayesian alternatives -- Bayes factor -- Bayesian false discovery probability (BFDP).
Access restricted to subscribers.
Mode of access: World Wide Web.
1765 Henry Stewart Talks
Genetic Predisposition to Disease--epidemiology.
Whole-genome association studies practical advice and considerations / [electronic resource] : Mike Weale. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (47 min.) : color, sound). - Genetic epidemiology II : latest developments, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Genetic epidemiology II : latest developments. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: What are whole-genome (genome-wide) association studies and why do them? -- Steps in WGA study -- HIV setpoint -- Phenotype definition -- Setpoint -- Whole genome genotyping panels -- PLINK -- Cryptic population stratification -- PCA and EIGENSTRAT -- SNP-by-SNP analysis -- Multiple testing approaches -- Bonferroni method -- Q-Q (quantile-quantile) plot -- False discovery rate -- Permutation -- Outright hits -- Pool of hits -- Bayesian alternatives -- Bayes factor -- Bayesian false discovery probability (BFDP).
Access restricted to subscribers.
Mode of access: World Wide Web.
1765 Henry Stewart Talks
Genetic Predisposition to Disease--epidemiology.