Epigenetic biomarkers in cancer [electronic resource] / Bob Brown.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Biomarkers: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Cancer -- Genetic aspects | DNA -- Methylation | Epigenesis | Tumor markers | DNA Methylation | Epigenesis, Genetic | Neoplasms -- drug therapy | Neoplasms -- genetics | Tumor Markers, Biological -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Epigenetics -- levels of control -- The patient cancer journey-multiple impact points -- Key translational areas for epigenetics -- DNA methylation as cancer biomarker -- DNA methylation analysis methods -- Epigenetic gene silencing in malignant cells -- CpG methylation and clinical outcome -- Causes of aberrant DNA methylation in cancer -- Stem cell targets -- EZH2 as a potential anti-cancer target -- Epigenetic modification as drug targets -- Epigenetic therapies -- DNA methylation versus platinum resistance -- Phase II trial of Decitabine & Carboplatin -- Effects of low doses of DNA-demethylation agents -- Epigenetic therapies challenges.
Access restricted to subscribers.
Mode of access: World Wide Web.