Structural and mechanistic insights into the neurotensin receptor [electronic resource] / Reinhard Grisshammer.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (55 min.) : color, sound)Subject(s): Cellular signal transduction | G proteins -- Receptors | Molecular structure | Neurotensin | Molecular Dynamics Simulation | Neurotensin -- chemistry | Neurotensin -- metabolism | Protein Conformation | Receptors, G-Protein-Coupled | Receptors, Neurotensin -- chemistry | Receptors, Neurotensin -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: G protein-coupled receptors -- Neurotensin receptor -- Peptide agonist neurotensin tools for crystallization of membrane proteins -- Conformational thermostabilization -- Crystal structure of NTSR1-GW5 -- Binding mode of neurotensin -- Crystal structures of NTSR1-ELF & NTSR1-LF-prerequisites for G protein activation -- Crystal structure of NTSR1-EL -- Constitutive activity -- Molecular dynamics simulations.
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Mode of access: World Wide Web.