Grisshammer, R. K.

Structural and mechanistic insights into the neurotensin receptor [electronic resource] / Reinhard Grisshammer. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (55 min.) : color, sound). - G Protein-Coupled Receptors (GPCRs) signaling in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: G protein-coupled receptors -- Neurotensin receptor -- Peptide agonist neurotensin tools for crystallization of membrane proteins -- Conformational thermostabilization -- Crystal structure of NTSR1-GW5 -- Binding mode of neurotensin -- Crystal structures of NTSR1-ELF & NTSR1-LF-prerequisites for G protein activation -- Crystal structure of NTSR1-EL -- Constitutive activity -- Molecular dynamics simulations.

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Mode of access: World Wide Web.

4771 Henry Stewart Talks


Cellular signal transduction.
G proteins--Receptors.
Molecular structure.
Neurotensin.
Molecular Dynamics Simulation.
Neurotensin--chemistry.
Neurotensin--metabolism.
Protein Conformation.
Receptors, G-Protein-Coupled.
Receptors, Neurotensin--chemistry.
Receptors, Neurotensin--metabolism.
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