Cocaine and amphetamine addiction genetics [electronic resource] / Gerome Breen.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): Pharmacogenetics | Psychopharmacology | Psychotropic DrugsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Heritability of cocaine and other addictions -- Gene-environment interactions and addiction -- The Dopamine transporter gene (SLC6A3) -- Brazilian Cocaine Association sample -- Case-control cohort from Sao Paulo, Brazil -- Association between the variants and cocaine addiction -- Potential study confounders -- Correcting for population stratification -- Reporter-gene assays indicating that the VNTR is a differential response element -- Functional assay of associated genetic variation -- Different expression levels of the alleles -- Allele and genotype association between DAT-intron 8 VNTR and cocaine -- Similar studies on amphetamine and methamphetamine addiction.
Access restricted to subscribers.
Mode of access: World Wide Web.