Breen, Gerome.

Cocaine and amphetamine addiction genetics [electronic resource] / Gerome Breen. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (33 min.) : color, sound). - Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Heritability of cocaine and other addictions -- Gene-environment interactions and addiction -- The Dopamine transporter gene (SLC6A3) -- Brazilian Cocaine Association sample -- Case-control cohort from Sao Paulo, Brazil -- Association between the variants and cocaine addiction -- Potential study confounders -- Correcting for population stratification -- Reporter-gene assays indicating that the VNTR is a differential response element -- Functional assay of associated genetic variation -- Different expression levels of the alleles -- Allele and genotype association between DAT-intron 8 VNTR and cocaine -- Similar studies on amphetamine and methamphetamine addiction.

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Mode of access: World Wide Web.

1239 Henry Stewart Talks


Pharmacogenetics.
Psychopharmacology.
Psychotropic Drugs.
Technical University of Mombasa
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