What can we learn from conformational profiling of GPCRs? [electronic resource] / Terry Hébert.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease: Publisher: London : Henry Stewart Talks, 2020Description: 1 online resource (1 streaming video file (68 min.) : color, sound)Subject(s): Cellular signal transduction | Drug development -- Methodology | G proteins -- Receptors | Proteins -- Conformation | Chemistry, Pharmaceutical -- methods | Chemistry, Pharmaceutical -- trends | Drug Discovery -- methods | Protein Conformation | Receptors, G-Protein-Coupled -- chemistry | Receptors, G-Protein-Coupled -- metabolism | Signal Transduction -- drug effects | Signal Transduction -- physiology | Technology, Pharmaceutical -- methodsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Biased signaling will have an impact in clinical medicine -- Pharma is moving into using signaling signatures to capture information during drug discovery process -- The information of signaling signatures can never be "complete" -- Conformational profiling may offer a huge time savings rather than extending signaling signatures -- Conformational profiling needs to be done in relevant cell, tissue and animal models.
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Mode of access: World Wide Web.