Hébert, Terry,
What can we learn from conformational profiling of GPCRs? [electronic resource] / Terry Hébert. - London : Henry Stewart Talks, 2020. - 1 online resource (1 streaming video file (68 min.) : color, sound). - G Protein-Coupled Receptors (GPCRs) signaling in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Biased signaling will have an impact in clinical medicine -- Pharma is moving into using signaling signatures to capture information during drug discovery process -- The information of signaling signatures can never be "complete" -- Conformational profiling may offer a huge time savings rather than extending signaling signatures -- Conformational profiling needs to be done in relevant cell, tissue and animal models.
Access restricted to subscribers.
Mode of access: World Wide Web.
5105 Henry Stewart Talks
Cellular signal transduction.
Drug development--Methodology.
G proteins--Receptors.
Proteins--Conformation.
Chemistry, Pharmaceutical--methods.
Chemistry, Pharmaceutical--trends.
Drug Discovery--methods.
Protein Conformation.
Receptors, G-Protein-Coupled--chemistry.
Receptors, G-Protein-Coupled--metabolism.
Signal Transduction--drug effects.
Signal Transduction--physiology.
Technology, Pharmaceutical--methods.
What can we learn from conformational profiling of GPCRs? [electronic resource] / Terry Hébert. - London : Henry Stewart Talks, 2020. - 1 online resource (1 streaming video file (68 min.) : color, sound). - G Protein-Coupled Receptors (GPCRs) signaling in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Biased signaling will have an impact in clinical medicine -- Pharma is moving into using signaling signatures to capture information during drug discovery process -- The information of signaling signatures can never be "complete" -- Conformational profiling may offer a huge time savings rather than extending signaling signatures -- Conformational profiling needs to be done in relevant cell, tissue and animal models.
Access restricted to subscribers.
Mode of access: World Wide Web.
5105 Henry Stewart Talks
Cellular signal transduction.
Drug development--Methodology.
G proteins--Receptors.
Proteins--Conformation.
Chemistry, Pharmaceutical--methods.
Chemistry, Pharmaceutical--trends.
Drug Discovery--methods.
Protein Conformation.
Receptors, G-Protein-Coupled--chemistry.
Receptors, G-Protein-Coupled--metabolism.
Signal Transduction--drug effects.
Signal Transduction--physiology.
Technology, Pharmaceutical--methods.