Inhibiting protein-protein interactions [electronic resource] : part 2 of 2 / Adrian Whitty.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Small molecule drug discovery: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (35 min.) : color, sound)Other title: Inhibiting protein-protein interactions. Part 2Subject(s): Drug development | Drug targeting | Protein-protein interactions | Proteins -- Inhibitors | Drug Design | Drug Discovery | Protein Binding -- drug effects | Protein Interaction Mapping | Proteins -- antagonists & inhibitors | Proteins -- metabolism | Small Molecule Libraries -- pharmacologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: A different view of druggability -- Five propositions about the druggability of PPI targets -- Protein-ligand binding energy -- Ligand efficiency and drug-target binding -- ADME & druglikeness considerations -- Conventional view of druglikeness -- Druggability and chemical space -- Targeting low druggability PPI -- Macrocycles -- Covalent inhibitors -- Foldamers.
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Mode of access: World Wide Web.