Whitty, Adrian,
Inhibiting protein-protein interactions part 2 of 2 / [electronic resource] : Inhibiting protein-protein interactions. Part 2 Adrian Whitty. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (35 min.) : color, sound). - Small molecule drug discovery, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: A different view of druggability -- Five propositions about the druggability of PPI targets -- Protein-ligand binding energy -- Ligand efficiency and drug-target binding -- ADME & druglikeness considerations -- Conventional view of druglikeness -- Druggability and chemical space -- Targeting low druggability PPI -- Macrocycles -- Covalent inhibitors -- Foldamers.
Access restricted to subscribers.
Mode of access: World Wide Web.
3718 Henry Stewart Talks
Drug development.
Drug targeting.
Protein-protein interactions.
Proteins--Inhibitors.
Drug Design.
Drug Discovery.
Protein Binding--drug effects.
Protein Interaction Mapping.
Proteins--antagonists & inhibitors.
Proteins--metabolism.
Small Molecule Libraries--pharmacology.
Inhibiting protein-protein interactions part 2 of 2 / [electronic resource] : Inhibiting protein-protein interactions. Part 2 Adrian Whitty. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (35 min.) : color, sound). - Small molecule drug discovery, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Small molecule drug discovery. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: A different view of druggability -- Five propositions about the druggability of PPI targets -- Protein-ligand binding energy -- Ligand efficiency and drug-target binding -- ADME & druglikeness considerations -- Conventional view of druglikeness -- Druggability and chemical space -- Targeting low druggability PPI -- Macrocycles -- Covalent inhibitors -- Foldamers.
Access restricted to subscribers.
Mode of access: World Wide Web.
3718 Henry Stewart Talks
Drug development.
Drug targeting.
Protein-protein interactions.
Proteins--Inhibitors.
Drug Design.
Drug Discovery.
Protein Binding--drug effects.
Protein Interaction Mapping.
Proteins--antagonists & inhibitors.
Proteins--metabolism.
Small Molecule Libraries--pharmacology.