Modulating gene expression to treat diseases [electronic resource] / Navneet Matharu.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2021Description: 1 online resource (1 streaming video file (20 min.) : color, sound)Subject(s): CRISPR (Genetics) | Gene expression | Gene targeting | Gene therapy | Medical genetics | Molecular genetics | Basic Helix-Loop-Helix Transcription Factors | Clustered Regularly Interspaced Short Palindromic Repeats | CRISPR-Cas Systems | Gene Expression Regulation | Gene Targeting -- methods | Genetic Diseases, Inborn -- therapy | Haploinsufficiency | Loss of Function Mutation | Obesity -- genetics | Obesity -- therapy | Receptor, Melanocortin, Type 4 | Repressor Proteins | Up-RegulationOnline resources: Click here to access online Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Programmable DNA targeting modules -- Effector domain functions and possibilities -- Haploinsufficiency and its role in disease -- CRISPRa targeting strategy to rescue Sim1 obesity -- CRISPRa targeting strategy to treat Mc4r haploinsufficiency.
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Mode of access: World Wide Web.