Invasion, metastasis and stem cells [electronic resource] / Robert Weinberg.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (39 min.) : color, sound)Subject(s): Neoplasm Metastasis -- physiopathology | Neoplastic Stem CellsOnline resources: Click here to access online Animated audio-visual presentation with synchonized narration.
Title from title frames.
Contents: Vogelstein-Kinzler model of multi-step colon cancer pathogenesis -- Cell of origin determines tumor morphology and behaviour -- Hierarchical organization of normal epithelial tissues -- Similar hierarchical organization of cancer cells in a tumor -- The invasion-metastasis cascade -- Physical dissemination -- Adaptation to and proliferation in a foreign tissue -- Colonization -- Epithelial-mesenchymal transition (EMT) -- The microenvironment of the primary tumor -- Twist transcription factor -- Slug TF -- What is the nature of cells generated by an EMT? -- EMT and cancer progression.
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Mode of access: World Wide Web.