Weinberg, Robert A. 1942-

Invasion, metastasis and stem cells [electronic resource] / Robert Weinberg. - London : Henry Stewart Talks, 2009. - 1 online resource (1 streaming video file (39 min.) : color, sound). - The biomedical & life sciences collection, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. .

Animated audio-visual presentation with synchonized narration. Title from title frames.

Contents: Vogelstein-Kinzler model of multi-step colon cancer pathogenesis -- Cell of origin determines tumor morphology and behaviour -- Hierarchical organization of normal epithelial tissues -- Similar hierarchical organization of cancer cells in a tumor -- The invasion-metastasis cascade -- Physical dissemination -- Adaptation to and proliferation in a foreign tissue -- Colonization -- Epithelial-mesenchymal transition (EMT) -- The microenvironment of the primary tumor -- Twist transcription factor -- Slug TF -- What is the nature of cells generated by an EMT? -- EMT and cancer progression.

Access restricted to subscribers.


Mode of access: World Wide Web.

2337 Henry Stewart Talks


Neoplasm Metastasis--physiopathology.
Neoplastic Stem Cells.
Technical University of Mombasa
Tom Mboya Street, Tudor 90420-80100 , Mombasa Kenya
Tel: (254)41-2492222/3 Fax: 2490571