Monoclonal antibodies and the ErbB system in human cancer [electronic resource] / Mark I. Greene.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (41 min.) : color, sound)Subject(s): Breast -- Cancer -- Immunotherapy | Cancer cells | Cell transformation | Monoclonal antibodies | Oncogenes | Antibodies, Monoclonal -- therapeutic use | Breast Neoplasms -- drug therapy | Breast Neoplasms -- immunology | Breast Receptor, ErbB-2 -- antagonists & inhibitors | Breast Receptor, ErbB-2 -- immunology | Breast Receptor, ErbB-2 -- physiology | EGFR protein, human | ErbB Receptors | Neoplasms -- drug therapy | Protein-Tyrosine Kinases | TrastuzumabOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: General properties of tumor cells -- Human breast cancer and the erbB2/neu oncogene and protein -- Targeted monoclonal antibodies -- Tyrosine kinase activity and dimerization -- Activation of the kinase of erbB2/neu -- Overexpression of erbB2/neu and EGFr -- The erbB family members -- Discussion of Herceptin -- Prevention of tumor growth in a neoadjuvant model -- Two antibody therapy & tumor growth inhibition.
Access restricted to subscribers.
Mode of access: World Wide Web.