Greene, Mark I.

Monoclonal antibodies and the ErbB system in human cancer [electronic resource] / Mark I. Greene. - London : Henry Stewart Talks, 2019. - 1 online resource (1 streaming video file (41 min.) : color, sound). - Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances. .

Animated audio-visual presentation with synchronized narration. Title from title frames. Updated version of a talk first published in 2007.

Contents: General properties of tumor cells -- Human breast cancer and the erbB2/neu oncogene and protein -- Targeted monoclonal antibodies -- Tyrosine kinase activity and dimerization -- Activation of the kinase of erbB2/neu -- Overexpression of erbB2/neu and EGFr -- The erbB family members -- Discussion of Herceptin -- Prevention of tumor growth in a neoadjuvant model -- Two antibody therapy & tumor growth inhibition.

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Mode of access: World Wide Web.

1309 Henry Stewart Talks


Breast--Cancer--Immunotherapy.
Cancer cells.
Cell transformation.
Monoclonal antibodies.
Oncogenes.
Antibodies, Monoclonal--therapeutic use.
Breast Neoplasms--drug therapy.
Breast Neoplasms--immunology.
Breast Receptor, ErbB-2--antagonists & inhibitors.
Breast Receptor, ErbB-2--immunology.
Breast Receptor, ErbB-2--physiology.
EGFR protein, human.
ErbB Receptors.
Neoplasms--drug therapy.
Protein-Tyrosine Kinases.
Trastuzumab.
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