Organellar calcium pumps of the golgi and ER [electronic resource] : from yeast to human / Rajini Rao.
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FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Calcium signaling I: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (31 min.) : color, sound)Subject(s): Calcium Signaling | Golgi ApparatusOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
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Contents: Early and current views on Calcium signaling -- Phylogenetic tree of Calcium-ATPases -- Identification of a new family of Golgi/secretory pathway Calcium-ATPases (SPCA) -- Why have a Calcium pump in the Golgi? -- Yeast as a model to understand Golgi Calcium pumps -- Biochemical characterization of Calcium and Mn2+ transport -- Phenotype screening in yeast to identify residues important for ion transport and selectivity in Pmr1 -- Structural and homology models of Calcium-ATPases -- Golgi pumps in mammals -- From structure to physiology -- Haploinsufficiency of ATP2C1 leads to Hailey Hailey disease -- Insights from yeast -- Distribution and localization of SPCA1 and SPCA2.
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Mode of access: World Wide Web.