Rao, Rajini.

Organellar calcium pumps of the golgi and ER from yeast to human / [electronic resource] : Rajini Rao. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (31 min.) : color, sound). - Calcium signaling I : regulation, mechanisms, effectors, role in disease and recent advances, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Calcium signaling I. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Early and current views on Calcium signaling -- Phylogenetic tree of Calcium-ATPases -- Identification of a new family of Golgi/secretory pathway Calcium-ATPases (SPCA) -- Why have a Calcium pump in the Golgi? -- Yeast as a model to understand Golgi Calcium pumps -- Biochemical characterization of Calcium and Mn2+ transport -- Phenotype screening in yeast to identify residues important for ion transport and selectivity in Pmr1 -- Structural and homology models of Calcium-ATPases -- Golgi pumps in mammals -- From structure to physiology -- Haploinsufficiency of ATP2C1 leads to Hailey Hailey disease -- Insights from yeast -- Distribution and localization of SPCA1 and SPCA2.

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1375 Henry Stewart Talks


Calcium Signaling.
Golgi Apparatus.
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