Store-operated Ca2+ entry and vascular smooth muscle remodeling [electronic resource] / Mohamed Trebak.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Calcium signaling II: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (49 min.) : color, sound)Subject(s): Calcium channels | Calcium -- Metabolism | Cellular signal transduction | Vascular smooth muscle -- Physiology | Calcium Channels -- physiology | Calcium Signaling | Calcium -- metabolism | Muscle, Smooth, Vascular -- physiologyOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Store-operated Ca2+ entry (SOCE) -- Measuring SOCE -- The whole-cell current mediated by SOCE, ICRAC -- The molecular players and mechanisms of activation of SOCE -- Vascular Smooth muscle cell (VSMC) remodeling -- VSMC organization and function -- VSMC contribution to vascular disease -- VSMC remodeling in restenosis -- VSMC remodeling and expression of ion channel/transporters -- SOCE and VSMC remodeling -- Role of STIM1 and Orai1 in VSMC SOCE and ICRAC -- STIM1 and Orai1 upregulation in VSMC from injured rat carotid vessels -- Role of STIM1 and Orai1 in driving VSMC remodeling in vivo -- STIM1- and Orai1-mediated SOCE and NFAT activity in VSMC -- STIM1 and Orai1 and SOCE in response to the potent proliferative and migratory agonist, PDGF.
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Mode of access: World Wide Web.