Trebak, Mohamed,

Store-operated Ca2+ entry and vascular smooth muscle remodeling [electronic resource] / Mohamed Trebak. - London : Henry Stewart Talks, 2012. - 1 online resource (1 streaming video file (49 min.) : color, sound). - Calcium signaling II : calcium and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Calcium signaling II. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Store-operated Ca2+ entry (SOCE) -- Measuring SOCE -- The whole-cell current mediated by SOCE, ICRAC -- The molecular players and mechanisms of activation of SOCE -- Vascular Smooth muscle cell (VSMC) remodeling -- VSMC organization and function -- VSMC contribution to vascular disease -- VSMC remodeling in restenosis -- VSMC remodeling and expression of ion channel/transporters -- SOCE and VSMC remodeling -- Role of STIM1 and Orai1 in VSMC SOCE and ICRAC -- STIM1 and Orai1 upregulation in VSMC from injured rat carotid vessels -- Role of STIM1 and Orai1 in driving VSMC remodeling in vivo -- STIM1- and Orai1-mediated SOCE and NFAT activity in VSMC -- STIM1 and Orai1 and SOCE in response to the potent proliferative and migratory agonist, PDGF.

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Mode of access: World Wide Web.

3420 Henry Stewart Talks


Calcium channels.
Calcium--Metabolism.
Cellular signal transduction.
Vascular smooth muscle--Physiology.
Calcium Channels--physiology.
Calcium Signaling.
Calcium--metabolism.
Muscle, Smooth, Vascular--physiology.
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