Ubiquitination and Alzheimer related disorders [electronic resource] : new insights and possible therapeutic approaches! / John Mayer.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Neurodegenerative diseases : fundamentals, research methods, latest advances: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (12 min.) : color, sound)Subject(s): Alzheimer Disease | Neurodegenerative Diseases | Ubiquitin -- therapeutic use | UbiquitinationOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin and the ubiquitin pathway of intracellular proteolysis -- Ubiquitin immunocytochemistry in understanding chronic neurodegenerative disease -- Ubiquitin and the discovery of dementia with Lewy bodies -- Importance of ubiquitin for normal brain functions -- Ubiquitin and Parkinson's disease -- Intraneuronal protein aggregation and neurodegenerative disease -- Experimental demonstration of generic gene expression changes in response to protein aggregates -- Expression of the mitogen activated protein kinase (MEK5) -- ERK5 kinase module in Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin-p62-MEK5/ERK5 pathway of neuronal survival in Alzheimer related disorders -- Diagnostic and therapeutic importance of ubiquitin/kinase mediated neuronal survival and anti-apoptotic pathways.
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Mode of access: World Wide Web.