The structural basis for how the large ribosomal subunit catalyses peptide bond formation [electronic resource] / Thomas A. Steitz.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (42 min.) : color, sound)Subject(s): Protein Biosynthesis | Ribosomal Proteins | RibosomesOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction.
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Mode of access: World Wide Web.