Steitz, Thomas A.

The structural basis for how the large ribosomal subunit catalyses peptide bond formation [electronic resource] / Thomas A. Steitz. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (42 min.) : color, sound). - The mechanisms of ribosome function : insights into protein synthesis, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction.

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Mode of access: World Wide Web.

1622 Henry Stewart Talks


Protein Biosynthesis.
Ribosomal Proteins.
Ribosomes.
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