Dendritic cells in asthma [electronic resource] / Bart N. Lambrecht.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Advances in asthma: Publisher: London : Henry Stewart Talks, 2013Description: 1 online resource (1 streaming video file (67 min.) : color, sound)Subject(s): Asthma -- Immunological aspects | Dendritic cells | Asthma -- immunology | Asthma -- pathology | Dendritic Cells -- immunologyOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The global immune response of the lungs -- Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation -- Controlling responsiveness to the node T cell area & Immunological synapse formation -- Peptide presentation by MHC class II molecules -- Cascade of costimulatory events -- Th2 lymphocytes role in airway inflammation -- Targeting DCs -- Allergen exposure activation -- Epithelial vs. DC expression of TLR4 -- Metabolic alterations -- Uric acid and antigen sensitisation in mice -- DC depletion -- Basement membrane thickening in asthma -- Model of chronic airway remodelling in the lungs -- Collagen deposition & antigen uptake/recognition -- Presentation of neoantigen.
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Mode of access: World Wide Web.