Lambrecht, Bart N.

Dendritic cells in asthma [electronic resource] / Bart N. Lambrecht. - London : Henry Stewart Talks, 2013. - 1 online resource (1 streaming video file (67 min.) : color, sound). - Advances in asthma : new mechanisms, management strategies and treatments, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Advances in asthma. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: The global immune response of the lungs -- Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation -- Controlling responsiveness to the node T cell area & Immunological synapse formation -- Peptide presentation by MHC class II molecules -- Cascade of costimulatory events -- Th2 lymphocytes role in airway inflammation -- Targeting DCs -- Allergen exposure activation -- Epithelial vs. DC expression of TLR4 -- Metabolic alterations -- Uric acid and antigen sensitisation in mice -- DC depletion -- Basement membrane thickening in asthma -- Model of chronic airway remodelling in the lungs -- Collagen deposition & antigen uptake/recognition -- Presentation of neoantigen.

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Mode of access: World Wide Web.

3274 Henry Stewart Talks


Asthma--Immunological aspects.
Dendritic cells.
Asthma--immunology.
Asthma--pathology.
Dendritic Cells--immunology.
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