The role of phosphorylation in mediating cellular responses to DNA damage [electronic resource] : the ATM-mediated DNA damage response / Yosef Shiloh.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein phosphorylation: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (62 min.) : color, sound)Subject(s): DNA damage | Phosphorylation | DNA Damage | DNA Repair | Phosphoproteins -- physiology | PhosphorylationOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
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Contents: Endogenous DNA damage in mammalian cells -- DSB repair pathways -- Cellular responses to DNA damage -- Genomic instability syndromes -- Ataxia-telangiectasia -- The ATM protein -- ATM-mediated DNA damage responses -- A SPIKE map -- Defective repair of DNA double strand breaks -- Allowing repair to happen within chromatin -- DNA damage response and the ubiquitin family -- Players in ubiquitin-related processes -- Phosphoproteome dynamics after DNA damage -- Functional networks of phosphorylated proteins -- Overlap between Ub, ATM and phosporylation -- Functional screens for novel DDR players.
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Mode of access: World Wide Web.