Similarities between prion diseases and other neurodegenerative diseases [electronic resource] / John Hardy.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (48 min.) : color, sound)Subject(s): Amyloid | PrionsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Pathology of diseases -- Prion diseases -- The first family with a prion mutation: Creutzfeldt-Jacob disease -- Alzheimer's disease -- 7Mb duplication of locus around APP -- APP probably a locus for "sporadic" Alzheimer's disease -- Diseases with only Lewy bodies: Parkinson's disease and Lewy body dementia -- Iowa kindred structure -- alpha-synuclein -- Diseases with only Tau pathology -- The microtubule associated protein tau -- Evolution of human tau haplotypes -- Tagging SNPs selection -- More complex than just H1/H2 -- Association with PSP is driven by H1c allele -- Primary tauopathies -- "Prion-like " behaviour of A-beta -- Does the "spreading" of diseases reflect a less extreme version of infection? -- Alzheimer's disease is a neuroanatomical disease which "spreads" -- Parkinson's disease pathology also seems to spread -- MAPT and alpha-synuclein in the extracellular compartment?
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Mode of access: World Wide Web.