Hardy, John, 1954-
Similarities between prion diseases and other neurodegenerative diseases [electronic resource] / John Hardy. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (48 min.) : color, sound). - Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Pathology of diseases -- Prion diseases -- The first family with a prion mutation: Creutzfeldt-Jacob disease -- Alzheimer's disease -- 7Mb duplication of locus around APP -- APP probably a locus for "sporadic" Alzheimer's disease -- Diseases with only Lewy bodies: Parkinson's disease and Lewy body dementia -- Iowa kindred structure -- alpha-synuclein -- Diseases with only Tau pathology -- The microtubule associated protein tau -- Evolution of human tau haplotypes -- Tagging SNPs selection -- More complex than just H1/H2 -- Association with PSP is driven by H1c allele -- Primary tauopathies -- "Prion-like " behaviour of A-beta -- Does the "spreading" of diseases reflect a less extreme version of infection? -- Alzheimer's disease is a neuroanatomical disease which "spreads" -- Parkinson's disease pathology also seems to spread -- MAPT and alpha-synuclein in the extracellular compartment?
Access restricted to subscribers.
Mode of access: World Wide Web.
1855 Henry Stewart Talks
Amyloid.
Prions.
Similarities between prion diseases and other neurodegenerative diseases [electronic resource] / John Hardy. - London : Henry Stewart Talks, 2008. - 1 online resource (1 streaming video file (48 min.) : color, sound). - Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Pathology of diseases -- Prion diseases -- The first family with a prion mutation: Creutzfeldt-Jacob disease -- Alzheimer's disease -- 7Mb duplication of locus around APP -- APP probably a locus for "sporadic" Alzheimer's disease -- Diseases with only Lewy bodies: Parkinson's disease and Lewy body dementia -- Iowa kindred structure -- alpha-synuclein -- Diseases with only Tau pathology -- The microtubule associated protein tau -- Evolution of human tau haplotypes -- Tagging SNPs selection -- More complex than just H1/H2 -- Association with PSP is driven by H1c allele -- Primary tauopathies -- "Prion-like " behaviour of A-beta -- Does the "spreading" of diseases reflect a less extreme version of infection? -- Alzheimer's disease is a neuroanatomical disease which "spreads" -- Parkinson's disease pathology also seems to spread -- MAPT and alpha-synuclein in the extracellular compartment?
Access restricted to subscribers.
Mode of access: World Wide Web.
1855 Henry Stewart Talks
Amyloid.
Prions.