Whole-genome association studies [electronic resource] : practical advice and considerations / Mike Weale.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: What are whole-genome (genome-wide) association studies and why do them? -- Steps in WGA study -- HIV setpoint -- Phenotype definition -- Setpoint -- Whole genome genotyping panels -- PLINK -- Cryptic population stratification -- PCA and EIGENSTRAT -- SNP-by-SNP analysis -- Multiple testing approaches -- Bonferroni method -- Q-Q (quantile-quantile) plot -- False discovery rate -- Permutation -- Outright hits -- Pool of hits -- Bayesian alternatives -- Bayes factor -- Bayesian false discovery probability (BFDP).
Access restricted to subscribers.
Mode of access: World Wide Web.