Possible roles of mitochondrial biogenesis in aging [electronic resource] / Aubrey D. N. J. de Grey.

By: De Grey, Aubrey D. N. J, 1963- [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Mitochondrial biogenesis : processes, regulation, functions and disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Aging | Mitochondria -- geneticsOnline resources: Click here to access online | Series
Contents:
Contents: Oxidative phosphorylation -- The mitochondrial DNA -- Aging as the accumulation of damage -- Types of aging damage -- Types of damaged cells -- Survival of cells lacking oxidative phosphorylation -- The plasma membrane redox system -- Reductive hotspot hypothesis -- "Survival of the slowest" hypothesis -- Allotopic expression -- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins -- Ways to make these proteins allotopically expressible.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: Oxidative phosphorylation -- The mitochondrial DNA -- Aging as the accumulation of damage -- Types of aging damage -- Types of damaged cells -- Survival of cells lacking oxidative phosphorylation -- The plasma membrane redox system -- Reductive hotspot hypothesis -- "Survival of the slowest" hypothesis -- Allotopic expression -- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins -- Ways to make these proteins allotopically expressible.

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