De Grey, Aubrey D. N. J., 1963-
Possible roles of mitochondrial biogenesis in aging [electronic resource] / Aubrey D. N. J. de Grey. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Mitochondrial biogenesis : processes, regulation, functions and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Mitochondrial biogenesis : processes, regulation, functions and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Oxidative phosphorylation -- The mitochondrial DNA -- Aging as the accumulation of damage -- Types of aging damage -- Types of damaged cells -- Survival of cells lacking oxidative phosphorylation -- The plasma membrane redox system -- Reductive hotspot hypothesis -- "Survival of the slowest" hypothesis -- Allotopic expression -- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins -- Ways to make these proteins allotopically expressible.
Access restricted to subscribers.
Mode of access: World Wide Web.
1486 Henry Stewart Talks
Aging.
Mitochondria--genetics.
Possible roles of mitochondrial biogenesis in aging [electronic resource] / Aubrey D. N. J. de Grey. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (44 min.) : color, sound). - Mitochondrial biogenesis : processes, regulation, functions and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Mitochondrial biogenesis : processes, regulation, functions and disease. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: Oxidative phosphorylation -- The mitochondrial DNA -- Aging as the accumulation of damage -- Types of aging damage -- Types of damaged cells -- Survival of cells lacking oxidative phosphorylation -- The plasma membrane redox system -- Reductive hotspot hypothesis -- "Survival of the slowest" hypothesis -- Allotopic expression -- Hydrophobicity prevents allotopic expression of mitochondrially-encoded proteins -- Ways to make these proteins allotopically expressible.
Access restricted to subscribers.
Mode of access: World Wide Web.
1486 Henry Stewart Talks
Aging.
Mitochondria--genetics.