Elongation of protein synthesis [electronic resource] : structural basis of the peptide bond / Marina V. Rodnina.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (40 min.) : color, sound)Subject(s): DNA | Gene Expression Regulation | Proteins | Transcription FactorsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The ribosome -- Chemistry of peptide bond formation -- Structure of the peptidyl transferase center of the ribosome -- Structures of the catalytic subunit with reaction substrates and transition state analogs -- Induced fit in peptide bond formation and peptidyl-tRNA hydrolysis -- Reaction pathways of catalyzed and uncatalyzed reactions -- pH dependence of catalysis -- Entropic catalysis -- Role of active site residues -- Importance of 2' OH of A76 of the tRNA in the P site -- The mechanism of peptide bond formation.
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Mode of access: World Wide Web.