Rodnina, Marina V.
Elongation of protein synthesis structural basis of the peptide bond / [electronic resource] : Marina V. Rodnina. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (40 min.) : color, sound). - From DNA to proteins : the multiple levels of regulation, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: The ribosome -- Chemistry of peptide bond formation -- Structure of the peptidyl transferase center of the ribosome -- Structures of the catalytic subunit with reaction substrates and transition state analogs -- Induced fit in peptide bond formation and peptidyl-tRNA hydrolysis -- Reaction pathways of catalyzed and uncatalyzed reactions -- pH dependence of catalysis -- Entropic catalysis -- Role of active site residues -- Importance of 2' OH of A76 of the tRNA in the P site -- The mechanism of peptide bond formation.
Access restricted to subscribers.
Mode of access: World Wide Web.
1144 Henry Stewart Talks
DNA.
Gene Expression Regulation.
Proteins.
Transcription Factors.
Elongation of protein synthesis structural basis of the peptide bond / [electronic resource] : Marina V. Rodnina. - London : Henry Stewart Talks, 2007. - 1 online resource (1 streaming video file (40 min.) : color, sound). - From DNA to proteins : the multiple levels of regulation, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation. .
Animated audio-visual presentation with synchronized narration. Title from title frames.
Contents: The ribosome -- Chemistry of peptide bond formation -- Structure of the peptidyl transferase center of the ribosome -- Structures of the catalytic subunit with reaction substrates and transition state analogs -- Induced fit in peptide bond formation and peptidyl-tRNA hydrolysis -- Reaction pathways of catalyzed and uncatalyzed reactions -- pH dependence of catalysis -- Entropic catalysis -- Role of active site residues -- Importance of 2' OH of A76 of the tRNA in the P site -- The mechanism of peptide bond formation.
Access restricted to subscribers.
Mode of access: World Wide Web.
1144 Henry Stewart Talks
DNA.
Gene Expression Regulation.
Proteins.
Transcription Factors.