Turning genomic junk into treasure [electronic resource] : genetic engineering with the Sleeping Beauty transposon system / Zoltan Ivics.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gene transfer and gene therapy: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (59 min.) : color, sound)Subject(s): Gene therapy | Genetic engineering | Genetic transformation | Genetic vectors -- Therapeutic use | DNA Transposable Elements | Gene Knock-In Techniques | Gene Therapy -- methods | Gene Transfer Techniques | Genetic Engineering | Genetic Vectors -- therapeutic use | Genomics | Transformation, Genetic | Transposases -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Transposons can be viewed as natural DNA transfer vehicles -- Transposons are capable of efficient genomic insertion, similar to integrating viruses -- Transposition can be controlled by conditionally providing the transposase enzyme -- DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner -- Transposition opens up many avenues for genome manipulations in vertebrates -- Generation of transgenic cells and germline-transgenic animals using transposons -- The Sleeping Beauty synthetic transposon -- Clinical applications of the Sleeping Beauty system.
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Mode of access: World Wide Web.