Ivics, Zoltan,

Turning genomic junk into treasure genetic engineering with the Sleeping Beauty transposon system / [electronic resource] : Zoltan Ivics. - London : Henry Stewart Talks, 2014. - 1 online resource (1 streaming video file (59 min.) : color, sound). - Gene transfer and gene therapy, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Gene transfer and gene therapy. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Transposons can be viewed as natural DNA transfer vehicles -- Transposons are capable of efficient genomic insertion, similar to integrating viruses -- Transposition can be controlled by conditionally providing the transposase enzyme -- DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner -- Transposition opens up many avenues for genome manipulations in vertebrates -- Generation of transgenic cells and germline-transgenic animals using transposons -- The Sleeping Beauty synthetic transposon -- Clinical applications of the Sleeping Beauty system.

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Mode of access: World Wide Web.

3747 Henry Stewart Talks


Gene therapy.
Genetic engineering.
Genetic transformation.
Genetic vectors--Therapeutic use.
DNA Transposable Elements.
Gene Knock-In Techniques.
Gene Therapy--methods.
Gene Transfer Techniques.
Genetic Engineering.
Genetic Vectors--therapeutic use.
Genomics.
Transformation, Genetic.
Transposases--metabolism.
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