Mitochondria and calcium signaling in cell life and cell death [electronic resource] / Michael R. Duchen.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Mitochondria in health and disease: Publisher: London : Henry Stewart Talks, 2018Description: 1 online resource (1 streaming video file (39 min.) : color, sound)Subject(s): Calcium -- Metabolism | Calcium -- Physiological effect | Cell death | Cellular signal transduction | Mitochondria | Calcium Metabolism Disorders | Calcium Signaling | Cell Death | Cytosol -- metabolism | Mitochondria -- metabolism | Mitochondria -- physiology | Mitochondrial Membrane Transport Proteins | mitochondrial permeability transition pore | Neuromuscular Diseases | Oxidative Phosphorylation | PermeabilityOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target.
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Mode of access: World Wide Web.