Mitochondria and calcium signaling in cell life and cell death [electronic resource] / Michael R. Duchen.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target.
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Mode of access: World Wide Web.