Duchen, Michael R.

Mitochondria and calcium signaling in cell life and cell death [electronic resource] / Michael R. Duchen. - London : Henry Stewart Talks, 2018. - 1 online resource (1 streaming video file (39 min.) : color, sound). - Mitochondria in health and disease, 2056-452X . - Henry Stewart talks. Biomedical & life sciences collection. Mitochondria in health and disease. .

Animated audio-visual presentation with synchronized narration. Title from title frames.

Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target.

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Mode of access: World Wide Web.

4513 Henry Stewart Talks


Calcium--Metabolism.
Calcium--Physiological effect.
Cell death.
Cellular signal transduction.
Mitochondria.
Calcium Metabolism Disorders.
Calcium Signaling.
Cell Death.
Cytosol--metabolism.
Mitochondria--metabolism.
Mitochondria--physiology.
Mitochondrial Membrane Transport Proteins.
mitochondrial permeability transition pore.
Neuromuscular Diseases.
Oxidative Phosphorylation.
Permeability.
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